Thursday, November 15, 2012

Fwd: 23 month old with ?IFNgR Deficiency



---------- Forwarded message ----------
From: glenn reeves <glenn.reeves@gmail.com>
Date: Wed, Nov 14, 2012 at 8:28 PM
Subject: 23 month old with ?IFNgR Deficiency
To: ImmDefClin <glenn.reeves.lgidc@blogger.com>, ImmDefLab <glenn.reeves.lgidls@blogger.com>


Ben, post cam path, t-cell reconstitution may not necessarily be normal, so I would be careful implying that a total lymph count implies a normal cd4 count.

In addition, in adult non HIV non drug induced immune suppression NTMI relapses are common. This seems true in the Thai anti-ifn antibody PTs as well as the idiopathic disease largely in elderly women who haven't been shown as yet to have ifn-g pathway defects.

Dr Daman Langguth
MBChB FRACP, FRCPA
P:07 3377 8698
M:0414642282
F:07 3871 1877