The question was whether there were any reports of fatal angioedema related to ACE inhibitors.
Theo was trying to get an idea, much like a Calman chart, of ball-park estimates for death risk (apparently higher in African populations?[Dean DE, etal, J Forensic Sci. 2001;46(5):1239]).
Theo was trying to get an idea, much like a Calman chart, of ball-park estimates for death risk (apparently higher in African populations?[Dean DE, etal, J Forensic Sci. 2001;46(5):1239]).
Response from Daman Langguth: "No, though have had one pt get a percutaneous tracheostomy (not with my pen). I think there may be some ascertainment bias as those who die probably do so remotely or at home perhaps in their sleep?? - Daman"
For more information on this topic, as well as an example of a Calman chart, see below:
For more information on this topic, as well as an example of a Calman chart, see below:
|
Term used
|
Risk range
|
Example
A=adv events/yr
D=deaths/yr
|
Risk
|
|
High
|
1:10 to 1: 100
|
Transmission to susceptible household
contacts of measles and chickenpox (A)
|
1:1 to 1:2
|
|
|
|
Transmission of HIV from mother to
child (Europe) (A)
|
1:6
|
|
|
|
Gastrointestinal effects of antibiotics
(A)
|
1:10 to 1:20
|
|
Moderate
|
1:100 to 1:1,000
|
Smoking 10 cigarettes a day (D)
|
1:200
|
|
|
|
All natural causes, age 40 (D)
|
1:850
|
|
Low
|
1:1,000 to 1:10,000
|
All kinds of violence and poisoning (D)
|
1:3,300
|
|
|
|
Influenza (D)
|
1:5,000
|
|
|
|
Accident on road (D)
|
1:8,000
|
|
Very low
|
1:10,000 to 1: 100,000
|
Leukaemia (D)
|
1:12,000
|
|
|
|
Playing football (D)
|
1:25,000
|
|
|
|
Accident at home (D)
|
1:26,000
|
|
|
|
Accident at work (D)
|
1:43,000
|
|
|
|
Homicide (D)
|
1:100,000
|
|
Minimal
|
1:100,000 to 1:1,000,000
|
Accident on railway (D)
|
1:500,000
|
|
|
|
Vaccination associated polio (A)
|
1:1,000,000
|
|
Negligible
|
<= 1:1,000,000
|
Hit by lightening (D)
|
1:10,000,000
|
|
|
|
Release of radiation by nuclear power
station
|
1:10,000,000
|
